Eggs meet
sperm, fertilization occurs, babies are formed. Simple? Not really! Get
introduced to the notion of feminine receptivity, or the freedom of choice for
women. Narrowing it further, the female eggs actually do choose. As believed by
Scott Gilbert, developmental biologist at Swarthmore College, the “egg engages
in a dialog with the sperm rather than locking it down.”
So,
fertilization is not actually a conquest, but more like a fair race. After much
research, it has also been proven that eggs tend to attract a particular kind
of sperm if given the chance. We’re thrilled to have come across the research
that proved that eggs can be choosy and have their own pick as far as sperm are
concerned.
The popular
notion — the race of the sperm
Any couple
who is planning to extend their family is always under the belief that the
sperm races toward the egg. Let’s start at the beginning. All sperm ready, egg
at its healthiest, and here begins the race! As we have been taught in school,
millions of sperm head towards a single egg cell. When an X meets an X, it’s a
girl, and when an X meets a Y, it’s a boy.
So, let’s
now begin the process of unlearning.
Female eggs
refuse to be submissive. They play a dominant role and choose their own sperm.
Race? Oh
wait! It was never a race since the winner has already been decided. In simple
language, the egg has already chosen the type of sperm that it will allow to
enter. As researched and explained by scientist Dr. Joseph H. Nadeau, eggs are
not submissive and docile, but a key player in the process of reproduction. And
against the popular notion that sperm races toward the egg, it’s actually the
other way around.
As explained
by Pacific Northwest Research Institute, it’s the egg that favors or discards a
sperm, and makes sexual selection at the cellular level itself more complex.
It’s strange but true that such an obvious process was assessed wrongly all
this time.
How Mendel’s
law was defied?
Mendel’s
Law, by definition, is the law of segregation. It’s also called the law of
inheritance according to which each parent carries 2 copies of each gene. The
next step is the ’random fertilization’ process in which these genes are
divided randomly into gametes that carry only one copy. However, recent studies
discarded this belief altogether.
Dr. Nadeau
conducted 2 separate experiments that hinted towards a different theory. His
intention was to produce specific predictable ratios of gene combinations in
offspring (based on Mendel’s laws). However, he couldn’t achieve it. As a part
of his experiment, he first gave female mice one normal and one mutant gene
that increased chances of getting testicular cancer. Male mice had all normal
genes. The result was in accordance with Mendel’s law.
Experiment
2: this time Dr. Nadeau reversed the breeding. He gave the male mice the mutant
cancerous gene, while females had all normal genes. And there it was! He was
astonished to see that only 27% received the mutant version, while they were
expecting it to be 75%.
What we all
have been taught about normal and mutated versions of DND1 in the mother and
the father went absolutely off calculation. What he made out of all this was
terming fertilization as non-random and proving the existence of a mechanism
that allows the egg to choose the sperm with the normal instead of the mutated
gene. In scientific terms, they call it ’genetically biased fertilization’.
What does
this signify?
What does
this signify? Was this always like this and skipped the sharp eye of top
scientists? Dr. Nadeau gave reasons for this newly found theory. He believed
there could be two possibilities for this.
1.
Attraction between sperm and egg largely involves the molecule of folic acid.
Metabolism of B vitamin or folic acid is different in an egg and a sperm. These
very changes may be the deciding factor for the attraction between sperm and
egg.
2. Sperm are
already present in the female reproductive tract when they are headed towards
the egg. The egg may not be fully developed during this time. There’s a
possibility that the egg influences this cell-division so that its genes can
also be well-suited to the sperm.
We hope this
makes the picture a little more clear. Don’t you think this information should
be shared further too? Please share your views on this newly found knowledge.
Via
BrightSide
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